Progression of fibroadenoma to malignant phyllodes tumour in a 14-year female

Faridi, S.H and Siddiqui, B and Ahmad, S.S and Aslam, M. (2018) Progression of fibroadenoma to malignant phyllodes tumour in a 14-year female. Journal of the College of Physicians and Surgeons Pakistan, 28 (1). pp. 69-71. ISSN 1022386X

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Phyllodes tumours are uncommon breast tumours which account for less than 1% of all breast neoplasms. High-grademalignant phyllodes tumour is a very rare but aggressive breast malignancy and forms approximately 15-30% of all phyllodes tumours. The transformation of a benign fibroadenoma into a malignant phyllodes tumour in a teenaged female is even rarer. We report here an interesting case of malignant phyllodes tumour in a 14-year female patient who was operated twice previously with the diagnosis of complex fibroadenoma in the same breast. There was a large tumour involving whole of the breast and infiltrating the skin. The patient was operated and total mastectomy was done. Diagnosis was confirmed after histopathological examination and immunohistochemistry of the resected specimen. Patient received adjuvant radiotherapy and there was no recurrence on 6-month follow-up. Owing to the rare occurrence of malignant phyllodes tumour in this age group along with previous operations for complex fibroadenoma, this case is being reported here.

Item Type: Article
Uncontrolled Keywords: Adjuvant radiotherapy; Adolescent female; Complex fibroadenoma; Malignant phyllodes tumour; Mastectomy
Subjects: R Medicine > RD Surgery
Divisions: Faculties > Faculty of Medicine > J.N. Medical College > Department of Surgery
Depositing User: AMU Library
Date Deposited: 18 Jan 2018 07:02
Last Modified: 18 Jan 2018 07:46

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