Nanoparticle-based mycosis vaccine

Zubair, S. and Azhar, A. and Khan, N. and Ahmad, E. and Ajmal, M. and Owais, M. (2017) Nanoparticle-based mycosis vaccine. Methods in Molecular Biology, 1625. pp. 169-211. ISSN 10643745

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Abstract

Many diseases that were considered major affliction of mankind in the past have been successfully eradicated with introduction of appropriate vaccine strategies. In order to expedite new challenges coming up to deal with various infectious diseases, nano-particulate-based subunit vaccines seem to be the demand of ordeal. The nano-vaccines can find better scope for the diseases that were not rampant in the semi-advanced world few years back. For example in present-day circumstances that corroborate with advancement in the field of medical sciences in terms of cancer chemotherapy, organ transplantation, therapy of autoimmune diseases, etc.; along with prevalence of altogether unheard diseases such as HIV infection, people are at risk of infliction with many more pathogens. In this regard, development of an effective prophylactic strategy against many opportunistic infections primarily caused by fungal pathogens needs better understanding of host pathogen relation and role of active immunity against pathogenic fungi. In the present study, we have tried to decipher effectiveness of a nano-sized vaccine delivery system in imparting protection against fungal pathogens.

Item Type: Article
Uncontrolled Keywords: Antifungal vaccines; Cryptococcosis; Escheriosome; Fibrin; Fungal infections; Lipid vesicles; Liposome; Nanoparticles
Divisions: Centres > Interdisciplinary Biotechnology Unit
Depositing User: AMU Library
Date Deposited: 25 Jan 2018 04:46
Last Modified: 11 Feb 2018 12:58
URI: http://ir.amu.ac.in/id/eprint/10956

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