Concomitant presence of carcinoma of breast in a patient with early-onset cataract: First case report of a potential association

Faridi, S.H. and Singh, K.D. and Lodhi, M. (2017) Concomitant presence of carcinoma of breast in a patient with early-onset cataract: First case report of a potential association. Journal of Clinical and Diagnostic Research, 11 (5). PD05-PD07. ISSN 2249782X

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Official URL: http://jcdr.net/article_fulltext.asp?issn=0973-709...

Abstract

A recent nation-wide population based retrospective cohort study from Taiwan in 2014 suggested a propensity of developing breast cancer in young females with early-onset cataract. We report here a case of a young non-obese female who presented to us with a large lump in the right breast with skin nodules and bilateral painless progressive diminution of vision. Patient was diagnosed to be suffering from locally advanced carcinoma of right breast with axillary metastasis (Stage III B) and bilateral early-onset nuclear cataract. Patient was started on taxane and anthracycline based neoadjuvant chemotherapy and after three cycles of chemotherapy patient showed partial response (≈50% reduction of tumour mass). Patient underwent small incision cataract surgery in left eye after the first cycle of chemotherapy. However, the patient was lost before any operative intervention could be done as she died in a road traffic accident. Possible mechanism of development of breast cancer in patients with early-onset cataract is discussed. This is the first reported case of a patient of early–onset cataract developing breast cancer as well as the first reported case of concomitant presence of early-onset bilateral cataract with breast cancer.

Item Type: Article
Uncontrolled Keywords: Adjuvant chemoradiation; Anthracycline; Early-onset cataract; Locally advanced carcinoma breast; Modified radical mastectomy
Subjects: R Medicine > R Medicine (General)
Divisions: Faculties > Faculty of Medicine > J.N. Medical College > Department of Surgery
Depositing User: AMU Library
Date Deposited: 25 Jan 2018 10:48
Last Modified: 02 Feb 2018 04:54
URI: http://ir.amu.ac.in/id/eprint/10981

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